Small children. Promethazine/codeine shouldn't be Utilized in any child younger than twelve yrs of age or in a youngster younger than 18 years of age after a surgical procedures to get rid of their tonsils or adenoids (tonsillectomy and/or adenoidectomy). Sluggish or shallow respiration that can result in death may happen. 

Drug interactions, which include an increased incidence of extrapyramidal consequences, are actually reported when some MAOI and phenothiazines are made use of concomitantly.

Keep away from the use of Promethazine HCl and Codeine Phosphate Oral Option in adolescents twelve to eighteen yrs of age who have other possibility things that could boost their sensitivity towards the respiratory depressant consequences of codeine.

Drug interactions might change how your drugs operate or improve your threat for really serious Negative effects. This doc does not contain all doable drug interactions.

If you're using sustained-release tablets or capsules, swallow the medication complete. Usually do not crush, chew, or break the tablets or capsules. Doing this can ruin the long action of the drug and could enhance Unwanted effects.

Nursing moms using codeine can even have better morphine stages inside their breast milk If they're ultra-fast metabolizers. These increased amounts of morphine in breast milk may perhaps lead to daily life-threatening or lethal side effects in nursing infants. Instruct nursing moms to Look ahead to indications of morphine toxicity inside their infants which include elevated sleepiness (more than typical), problem breastfeeding, respiratory complications, or limpness.

Consider promethazine/codeine specifically as prescribed. Convey to your healthcare company for those who feel that promethazine/codeine is just not Doing the job. Phone your healthcare company right away or visit the nearest unexpected emergency home if you have any of the subsequent severe signs or symptoms.

1)]. All individuals handled with opioids call for watchful monitoring for indications of abuse and dependancy, considering that use of opioid analgesic and antitussive check here merchandise carries the potential risk of addiction even below proper professional medical use.

Disorders OF USE: The data in this databases read more is intended to complement, not substitute for, the expertise and judgment of healthcare pros. The data will not be intended to protect all possible read more makes use of, Instructions, safeguards, drug interactions or adverse outcomes, nor should really it be construed to point that usage of a selected drug is Risk-free, correct or effective for you personally or anybody else.

Warning patients that some people have a variation inside a liver enzyme and change codeine into morphine a lot more quickly and entirely than Others. These persons are ultra-speedy metabolizers and are more likely to have increased-than-usual amounts of morphine inside their blood soon after using codeine, which may end up in overdose signs for example Severe sleepiness, confusion, or shallow respiration. Generally, it's unknown if anyone can be an extremely-speedy codeine metabolizer.

See dosage Recommendations over or talk to the products label to find out the appropriate dosage for yourself.

Normally go through the label and only use as directed. If you're Not sure, speak to a healthcare Experienced.

Codeine has great antitussive exercise, While under that of morphine at equivalent doses. It truly is Utilized in preference to morphine, since Unwanted effects are infrequent at the usual antitussive dose of codeine.

As an example, numerous click here described situations of Dying transpired in the post-operative time period subsequent tonsillectomy and/or adenoidectomy, and several of the kids had evidence of currently being ultra-immediate metabolizers of codeine. Additionally, young children with obstructive sleep apnea that are treated with codeine for article-tonsillectomy and/or adenoidectomy discomfort may very well be notably delicate to its respiratory depressant result. Codeine Linctus Cough Syrup Due to the hazard of existence-threatening respiratory despair and death: